منابع مشابه
ACUTE EXTRAPYRAMIDAL SYMPTOMS FOLLOWING ABRUPT DISCONTINUATION OF PROPRANOLOL
A case of acute extrapyramidal manifestations consisting of dystonia and akathisia following abrupt discontinuation of propranolol is reported. She responded well to oral propranolol and intramuscular diazepam. Extrapyramidal symptoms have commonly been associated with acute or chronic administration of neuroleptic drugs. There have been reports of a substantial number of cases with simila...
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Warfarin is the traditional therapeutic option available to manage thromboembolic risk in atrial fibrillation. The hemorrhagic risk with warfarin depends mainly on the international normalized ratio (INR). Data from randomized controlled trials show that patients have a therapeutic INR (2.00-3.00) only 61%-68% of the time while taking warfarin, and this target is sometimes hard to establish. Ma...
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Novel oral anticoagulants (NOAC) are a group of drugs recently approved for the treatment of patients at high risk of arterial or venous thrombosis. Unlike vitamin K antagonists, NOAC have a faster onset of action, less drug interactions and do not need frequent monitoring, making their prescription more convenient for physicians and patients. However, both classes of drugs have the potential f...
متن کاملMassive human rivaroxaban overdose.
Thomas Lehmann1; Katharina E. Hofer2; Michael Baumann1; Karin Hasler3; Alessandro Ceschi2; Hugo Kupferschmidt2; Gabriele Rohde4; Wolfgang Korte1 1Center of Laboratory Medicine and Hemostasis and Hemophilia Center St. Gallen, St. Gallen, Switzerland; 2Swiss Toxicological Information Centre, Associated Institute of the Zurich University, Zurich, Switzerland; 3Department of Emergency, Kantonsspita...
متن کاملXarelto, INN-Rivaroxaban
The application submitted is a complete dossier composed of administrative information, complete quality data, non-clinical and clinical data based on applicants' own tests and studies and/or bibliographic literature substituting/supporting certain test(s) or study(ies) Licensing status: The product was not licensed in any country at the time of submission of the application. • The CHMP opinion...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2013
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2012.09.056